3QT2

Structure of a cytokine ligand-receptor complex

Summary for 3QT2

• Entry DOI: 10.2210/pdb3qt2/pdb
• Descriptor: Interleukin-5 receptor subunit alpha, Interleukin-5, beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: cytokine type i receptor fold, fibronectin type iii modules, four-helical bundle, cytokine, ligand-receptor complex, membrane, protein binding-immune system complex, protein binding/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 126908.43

Authors

Mueller, T.D.,Patino, E.,Kotzsch, A.,Saremba, S.,Nickel, J.,Schmitz, W.,Sebald, W. (deposition date: 2011-02-22, release date: 2012-02-01, Last modification date: 2020-07-29)

• Primary citation: Patino, E.,Kotzsch, A.,Saremba, S.,Nickel, J.,Schmitz, W.,Sebald, W.,Mueller, T.D.; Structure Analysis of the IL-5 Ligand-Receptor Complex Reveals a Wrench-like Architecture for IL-5Ralpha.; Structure, 19:1864-1875, 2011; PubMed: 22153509; DOI: 10.1016/j.str.2011.08.015

Experimental method

X-RAY DIFFRACTION (2.55 Å)