3QS6

Crystal structure of LeuT mutant F259V,I359Q bound to sodium and L-tryptophan

Summary for 3QS6

Entry DOI	10.2210/pdb3qs6/pdb
Related	2A65 3F3A 3QS4 3QS6
Descriptor	Na(+):neurotransmitter symporter (Snf family), TRYPTOPHAN, SODIUM ION, ... (5 entities in total)
Functional Keywords	nss, neurotransmitter transporter, leut-fold, sodium-coupled secondary transporter, sodium and amino acid binding, membrane, transport protein
Biological source	Aquifex aeolicus
Total number of polymer chains	1
Total formula weight	59171.68
Authors	Piscitelli, C.L.,Gouaux, E. (deposition date: 2011-02-19, release date: 2011-10-12, Last modification date: 2023-09-13)
Primary citation	Piscitelli, C.L.,Gouaux, E. Insights into transport mechanism from LeuT engineered to transport tryptophan. Embo J., 31:228-235, 2012 Cited by PubMed: 21952050 DOI: 10.1038/emboj.2011.353 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.801 Å)

Structure validation