3QR0
Crystal Structure of S. officinalis PLC21
Summary for 3QR0
Entry DOI | 10.2210/pdb3qr0/pdb |
Related | 3QR1 |
Descriptor | phospholipase C-beta (PLC-beta), CALCIUM ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | ph domain, ef hand, c2 domain, tim barrel domain, hydrolase, phospholipase, calcium binding, phospholipid binding |
Biological source | Sepia officinalis (cuttlefish) |
Total number of polymer chains | 1 |
Total formula weight | 93740.36 |
Authors | Lyon, A.M.,Northup, J.K.,Tesmer, J.J.G. (deposition date: 2011-02-16, release date: 2011-08-10, Last modification date: 2023-09-13) |
Primary citation | Lyon, A.M.,Tesmer, V.M.,Dhamsania, V.D.,Thal, D.M.,Gutierrez, J.,Chowdhury, S.,Suddala, K.C.,Northup, J.K.,Tesmer, J.J. An autoinhibitory helix in the C-terminal region of phospholipase C-beta mediates Galphaq activation. Nat.Struct.Mol.Biol., 18:999-1005, 2011 Cited by PubMed: 21822282DOI: 10.1038/nsmb.2095 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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