3QFT
Crystal Structure of NADPH-Cytochrome P450 Reductase (FAD/NADPH domain and R457H Mutant)
Summary for 3QFT
| Entry DOI | 10.2210/pdb3qft/pdb |
| Related | 3QE2 3QFC 3QFR 3QFS |
| Descriptor | NADPH--cytochrome P450 reductase, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total) |
| Functional Keywords | nadph-cytochrome p450 reductase, flavoprotein, antley-bixler syndrome, fad, nadph, oxidoreductase |
| Biological source | Homo sapiens (human) |
| Cellular location | Endoplasmic reticulum membrane; Peripheral membrane protein: P16435 |
| Total number of polymer chains | 1 |
| Total formula weight | 53512.98 |
| Authors | Xia, C.,Marohnic, C.,Panda, S.P.,Masters, B.S.,Kim, J.-J.P. (deposition date: 2011-01-22, release date: 2011-08-17, Last modification date: 2023-09-13) |
| Primary citation | Xia, C.,Panda, S.P.,Marohnic, C.C.,Martasek, P.,Masters, B.S.,Kim, J.J. Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency. Proc.Natl.Acad.Sci.USA, 108:13486-13491, 2011 Cited by PubMed: 21808038DOI: 10.1073/pnas.1106632108 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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