3Q2J

Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa Protein Kinase Inhibitor CKI-7 Complex

Summary for 3Q2J

Entry DOI	10.2210/pdb3q2j/pdb
Related	1J7I 1J7L 1J7U 1L8T 2B0Q 3H8P
Descriptor	Aminoglycoside 3'-phosphotransferase, CALCIUM ION, N-(2-AMINOETHYL)-5-CHLOROISOQUINOLINE-8-SULFONAMIDE, ... (4 entities in total)
Functional Keywords	ser/thr/tyr protein kinase, kinase, phosphorylation, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Enterococcus faecalis (Streptococcus faecalis)
Total number of polymer chains	2
Total formula weight	62675.75
Authors	Fong, D.H.,Xiong, B.,Hwang, J.,Berghuis, A.M. (deposition date: 2010-12-20, release date: 2011-05-18, Last modification date: 2023-09-13)
Primary citation	Fong, D.H.,Xiong, B.,Hwang, J.,Berghuis, A.M. Crystal structures of two aminoglycoside kinases bound with a eukaryotic protein kinase inhibitor. Plos One, 6:e19589-e19589, 2011 Cited by PubMed: 21573013 DOI: 10.1371/journal.pone.0019589 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1501 Å)

Structure validation