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3PX6

Crystal Structure of Bacillus DNA Polymerase I Large Fragment Bound to DNA and ddCTP-dA Mismatch (tautomer) in Closed Conformation

Summary for 3PX6
Entry DOI10.2210/pdb3px6/pdb
Related3PV8 3PX0 3PX4
DescriptorDNA polymerase I, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*C*AP*TP*AP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... (7 entities in total)
Functional Keywordsdna polymerase i, protein-dna complex, transferase-dna complex, cytosine-adenine, closed conformation, transferase/dna
Biological sourceGeobacillus kaustophilus
Total number of polymer chains6
Total formula weight150180.98
Authors
Wang, W.,Beese, L.S. (deposition date: 2010-12-09, release date: 2011-10-19, Last modification date: 2023-09-13)
Primary citationWang, W.,Hellinga, H.W.,Beese, L.S.
Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis.
Proc.Natl.Acad.Sci.USA, 108:17644-17648, 2011
Cited by
PubMed: 22006298
DOI: 10.1073/pnas.1114496108
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.59 Å)
Structure validation

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