3PV8

Crystal Structure of Bacillus DNA Polymerase I Large Fragment Bound to DNA and ddTTP-dA in Closed Conformation

Summary for 3PV8

• Entry DOI: 10.2210/pdb3pv8/pdb
• Related: 3PX0 3PX4 3PX6
• Descriptor: DNA polymerase I, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(2DT))-3'), DNA (5'-D(*C*AP*TP*AP*AP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... (7 entities in total)
• Functional Keywords: dna polymerase i, protein-dna complex, thymine-adenine, closed conformation, transferase-dna complex, transferase/dna
• Biological source: Geobacillus kaustophilus
• Total number of polymer chains: 6
• Total formula weight: 149600.54

Authors

Wang, W.,Beese, L.S. (deposition date: 2010-12-06, release date: 2011-10-19, Last modification date: 2023-09-06)

• Primary citation: Wang, W.,Hellinga, H.W.,Beese, L.S.; Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis.; Proc.Natl.Acad.Sci.USA, 108:17644-17648, 2011; PubMed: 22006298; DOI: 10.1073/pnas.1114496108

Experimental method

X-RAY DIFFRACTION (1.52 Å)