3POO

human cAMP-dependent protein kinase in complex with an inhibitor

Summary for 3POO

• Entry DOI: 10.2210/pdb3poo/pdb
• Related: 3NX8 3OOG 3OVV 3OWP 3OXT 3P0M
• Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, N'-[(E)-(2,4-dihydroxy-6-methylphenyl)methylidene]-2-(3-methoxyphenyl)acetohydrazide, ... (5 entities in total)
• Functional Keywords: atp binding, phosphorylation, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P17612
• Total number of polymer chains: 2
• Total formula weight: 43439.44

Authors

Koester, H.,Heine, A.,Klebe, G. (deposition date: 2010-11-23, release date: 2011-11-16, Last modification date: 2023-09-06)

• Primary citation: Koester, H.,Craan, T.,Heine, A.,Klebe, G.; fragment based drug design on PKA; To be Published,

Experimental method

X-RAY DIFFRACTION (1.6 Å)