3PNC

Ternary crystal structure of a polymerase lambda variant with a GT mispair at the primer terminus and sodium at catalytic metal site

Summary for 3PNC

• Entry DOI: 10.2210/pdb3pnc/pdb
• Related: 3PML 3PMN
• Descriptor: DNA polymerase lambda, 5'-D(*CP*AP*GP*TP*AP*G)-3', 5'-D(*CP*GP*GP*CP*CP*TP*TP*AP*CP*TP*G)-3', ... (9 entities in total)
• Functional Keywords: protein-dna complex, lyase, transferase, dna, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q9UGP5
• Total number of polymer chains: 4
• Total formula weight: 43806.90

Authors

Bebenek, K.,Pedersen, L.C.,Kunkel, T.A. (deposition date: 2010-11-18, release date: 2011-02-02, Last modification date: 2024-02-21)

• Primary citation: Bebenek, K.,Pedersen, L.C.,Kunkel, T.A.; Replication infidelity via a mismatch with Watson-Crick geometry.; Proc.Natl.Acad.Sci.USA, 108:1862-1867, 2011; PubMed: 21233421; DOI: 10.1073/pnas.1012825108

Experimental method

X-RAY DIFFRACTION (2 Å)