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3PNA

Crystal Structure of cAMP bound (91-244)RIa Subunit of cAMP-dependent Protein Kinase

Summary for 3PNA
Entry DOI10.2210/pdb3pna/pdb
Related1NE4 1RGS
DescriptorcAMP-dependent protein kinase type I-alpha regulatory subunit, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, ... (4 entities in total)
Functional Keywordsbeta-barrel, camp-binding, catalytic subunit, transferase
Biological sourceBos taurus (bovine,cow,domestic cattle,domestic cow)
Total number of polymer chains2
Total formula weight35429.63
Authors
Kim, C.,Taylor, S. (deposition date: 2010-11-18, release date: 2011-02-09, Last modification date: 2024-02-21)
Primary citationBadireddy, S.,Yunfeng, G.,Ritchie, M.,Akamine, P.,Wu, J.,Kim, C.W.,Taylor, S.S.,Qingsong, L.,Swaminathan, K.,Anand, G.S.
Cyclic AMP Analog Blocks Kinase Activation by Stabilizing Inactive Conformation: Conformational Selection Highlights a New Concept in Allosteric Inhibitor Design.
Mol Cell Proteomics, 10:M110.004390-M110.004390, 2011
Cited by
PubMed: 21081668
DOI: 10.1074/mcp.M110.004390
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.503 Å)
Structure validation

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