3PGL

Crystal structure of human small C-terminal domain phosphatase 1 (Scp1) bound to rabeprazole

Summary for 3PGL

Entry DOI	10.2210/pdb3pgl/pdb
Related	1T9Z 2GHQ 2GHT 3L0B 3L0C 3L0Y
Descriptor	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, 2-[(R)-{[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methyl}sulfinyl]-1H-benzimidazole, ... (4 entities in total)
Functional Keywords	had family, insertion domain, ctd phosphatase, neuronal silencer, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human)
Cellular location	Nucleus : Q9GZU7
Total number of polymer chains	2
Total formula weight	41887.24
Authors	Zhang, M.,Cho, E.J.,Burstein, G.,Siegel, D.,Zhang, Y. (deposition date: 2010-11-02, release date: 2011-03-09, Last modification date: 2024-02-21)
Primary citation	Zhang, M.,Cho, E.J.,Burstein, G.,Siegel, D.,Zhang, Y. Selective inactivation of a human neuronal silencing phosphatase by a small molecule inhibitor. Acs Chem.Biol., 6:511-519, 2011 Cited by PubMed: 21348431 DOI: 10.1021/cb100357t PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation