3PD0

Caspase-3 E246A

Summary for 3PD0

Entry DOI	10.2210/pdb3pd0/pdb
Related	3PCX 3PD1
Related PRD ID	PRD_000238
Descriptor	Caspase-3, INHIBITOR AC-DEVD-CMK, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	salt bridge, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P42574
Total number of polymer chains	2
Total formula weight	29166.97
Authors	Walters, J.,Swartz, P.,Mattos, C.,Clark, A.C. (deposition date: 2010-10-22, release date: 2011-02-16, Last modification date: 2012-12-12)
Primary citation	Walters, J.,Swartz, P.,Mattos, C.,Clark, A.C. Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3. Arch.Biochem.Biophys., 508:31-38, 2011 Cited by PubMed: 21266160 DOI: 10.1016/j.abb.2011.01.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation