3PCU
Crystal structure of human retinoic X receptor alpha ligand-binding domain complexed with LX0278 and SRC1 peptide
Summary for 3PCU
Entry DOI | 10.2210/pdb3pcu/pdb |
Descriptor | Retinoic acid receptor RXR-alpha, Nuclear receptor coactivator 2, 2-[(2S)-6-(2-methylbut-3-en-2-yl)-7-oxo-2,3-dihydro-7H-furo[3,2-g]chromen-2-yl]propan-2-yl acetate, ... (4 entities in total) |
Functional Keywords | nuclear receptor rxralpha, ligand-binding domain, transcription-transcription regulator complex, transcription/transcription regulator |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P19793 Q15596 |
Total number of polymer chains | 2 |
Total formula weight | 27400.85 |
Authors | |
Primary citation | Zhang, Y.,Zhang, H.,Yao, X.G.,Shen, H.,Chen, J.,Li, C.,Chen, L.,Zheng, M.,Ye, J.,Hu, L.,Shen, X.,Jiang, H. (+)-Rutamarin as a Dual Inducer of Both GLUT4 Translocation and Expression Efficiently Ameliorates Glucose Homeostasis in Insulin-Resistant Mice. Plos One, 7:e31811-e31811, 2012 Cited by PubMed: 22384078DOI: 10.1371/journal.pone.0031811 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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