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3PCU

Crystal structure of human retinoic X receptor alpha ligand-binding domain complexed with LX0278 and SRC1 peptide

Summary for 3PCU
Entry DOI10.2210/pdb3pcu/pdb
DescriptorRetinoic acid receptor RXR-alpha, Nuclear receptor coactivator 2, 2-[(2S)-6-(2-methylbut-3-en-2-yl)-7-oxo-2,3-dihydro-7H-furo[3,2-g]chromen-2-yl]propan-2-yl acetate, ... (4 entities in total)
Functional Keywordsnuclear receptor rxralpha, ligand-binding domain, transcription-transcription regulator complex, transcription/transcription regulator
Biological sourceHomo sapiens (human)
More
Cellular locationNucleus: P19793 Q15596
Total number of polymer chains2
Total formula weight27400.85
Authors
Zhang, H.,Zhang, Y.,Shen, H.,Chen, J.,Li, C.,Chen, L.,Hu, L.,Jiang, H.,Shen, X. (deposition date: 2010-10-22, release date: 2011-11-16, Last modification date: 2023-11-01)
Primary citationZhang, Y.,Zhang, H.,Yao, X.G.,Shen, H.,Chen, J.,Li, C.,Chen, L.,Zheng, M.,Ye, J.,Hu, L.,Shen, X.,Jiang, H.
(+)-Rutamarin as a Dual Inducer of Both GLUT4 Translocation and Expression Efficiently Ameliorates Glucose Homeostasis in Insulin-Resistant Mice.
Plos One, 7:e31811-e31811, 2012
Cited by
PubMed: 22384078
DOI: 10.1371/journal.pone.0031811
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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