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3P8X

Synthesis, Structure, and Biological Activity of des-Side Chain Analogues of 1alpha,25-Dihydroxyvitamin D3 with Substituents at C-18

Summary for 3P8X
Entry DOI10.2210/pdb3p8x/pdb
Related1DB1
DescriptorVitamin D3 receptor, (1R,3S,5Z)-5-{(2E)-2-[(3aR,7aS)-7a-(7-hydroxy-7-methyloctyl)octahydro-4H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol, SULFATE ION, ... (4 entities in total)
Functional Keywordshelices sandwich, transcription regulation, vitamin d, transcription regulator
Biological sourceHomo sapiens (human)
More
Cellular locationNucleus: P11473
Total number of polymer chains1
Total formula weight32303.18
Authors
Rochel, N.,Sato, Y.,Moras, D. (deposition date: 2010-10-15, release date: 2011-08-31, Last modification date: 2024-02-21)
Primary citationVerlinden, L.,Verstuyf, A.,Eelen, G.,Bouillon, R.,Ordonez-Moran, P.,Larriba, M.J.,Munoz, A.,Rochel, N.,Sato, Y.,Moras, D.,Maestro, M.,Seoane, S.,Dominguez, F.,Eduardo-Canosa, S.,Nicoletti, D.,Moman, E.,Mourino, A.
Synthesis, Structure, and Biological Activity of des-Side Chain Analogues of 1 ,25-Dihydroxyvitamin D3 with Substituents at C-18
Chemmedchem, 6:788-793, 2011
Cited by
PubMed: 21520419
DOI: 10.1002/cmdc.201100021
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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