3P8C

Structure and Control of the Actin Regulatory WAVE Complex

Summary for 3P8C

Entry DOI	10.2210/pdb3p8c/pdb
Descriptor	Cytoplasmic FMR1-interacting protein 1, Nck-associated protein 1, Wiskott-Aldrich syndrome protein family member 1, ... (9 entities in total)
Functional Keywords	actin polymerization, protein binding
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm : Q7L576 Cell membrane ; Single-pass membrane protein ; Cytoplasmic side : Q9Y2A7 Cytoplasm, cytoskeleton : Q92558 Q8WUW1
Total number of polymer chains	5
Total formula weight	333843.42
Authors	Chen, Z.,Borek, D.,Padrick, S.B.,Gomez, T.S.,Metlagel, Z.,Ismail, A.M.,Umetani, J.,Billadeau, D.D.,Otwinowski, Z.,Rosen, M.K. (deposition date: 2010-10-13, release date: 2010-12-01, Last modification date: 2024-02-21)
Primary citation	Chen, Z.,Borek, D.,Padrick, S.B.,Gomez, T.S.,Metlagel, Z.,Ismail, A.M.,Umetani, J.,Billadeau, D.D.,Otwinowski, Z.,Rosen, M.K. Structure and control of the actin regulatory WAVE complex. Nature, 468:533-538, 2010 Cited by PubMed: 21107423 DOI: 10.1038/nature09623 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.29 Å)

Structure validation