3OXU

Complement components factor H CCP19-20 and C3d in complex

Summary for 3OXU

• Entry DOI: 10.2210/pdb3oxu/pdb
• Related: 1C3D 2G7I
• Descriptor: Complement C3, HF protein, GLYCEROL, ... (4 entities in total)
• Functional Keywords: c3d-alpha-alpha barrel, complement component, factor h, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P01024
• Total number of polymer chains: 6
• Total formula weight: 151391.45

Authors

Morgan, H.P.,Schmidt, C.Q.,Guariento, M.,Gillespie, D.,Herbert, A.P.,Mertens, H.,Blaum, B.S.,Svergun, D.,Johansson, C.M.,Uhrin, D.,Barlow, P.N.,Hannan, J.P. (deposition date: 2010-09-22, release date: 2011-02-16, Last modification date: 2023-09-06)

• Primary citation: Morgan, H.P.,Schmidt, C.Q.,Guariento, M.,Blaum, B.S.,Gillespie, D.,Herbert, A.P.,Kavanagh, D.,Mertens, H.D.,Svergun, D.I.,Johansson, C.M.,Uhrin, D.,Barlow, P.N.,Hannan, J.P.; Structural basis for engagement by complement factor H of C3b on a self surface.; Nat.Struct.Mol.Biol., 18:463-470, 2011; PubMed: 21317894; DOI: 10.1038/nsmb.2018

Experimental method

X-RAY DIFFRACTION (2.1 Å)