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3OVN

Fragment-based approach to the design of ligands targeting a novel site on HIV-1 integrase

Summary for 3OVN
Entry DOI10.2210/pdb3ovn/pdb
Related3AO1 3AO2 3AO3 3AO4 3AO5 3l3u
Related PRD IDPRD_900003
DescriptorPOL polyprotein, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, SULFATE ION, ... (6 entities in total)
Functional Keywordsdna integration, aids, integrase, endonuclease, polynucleotidyl transferase, dna binding, viral protein, rnaseh, fragment binding, viral protein-transferase inhibitor complex, viral protein/transferase inhibitor
Biological sourceHuman immunodeficiency virus 1
Total number of polymer chains2
Total formula weight36946.90
Authors
Wielens, J.,Chalmers, D.K.,Headey, S.J.,Deadman, J.J.,Rhodes, D.K.,Parker, M.W.,Scanlon, M.J. (deposition date: 2010-09-16, release date: 2011-03-09, Last modification date: 2023-11-01)
Primary citationWielens, J.,Headey, S.J.,Deadman, J.J.,Rhodes, D.I.,Parker, M.W.,Chalmers, D.K.,Scanlon, M.J.
Fragment-based design of ligands targeting a novel site on the integrase enzyme of human immunodeficiency virus 1
Chemmedchem, 6:258-261, 2011
Cited by
PubMed: 21275048
DOI: 10.1002/cmdc.201000483
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

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