3OO5

R-state human hemoglobin: nitriheme modified

Summary for 3OO5

• Entry DOI: 10.2210/pdb3oo5/pdb
• Related: 3ONZ 3OO4
• Descriptor: Hemoglobin subunit alpha, Hemoglobin subunit beta, [3,3'-{7-ethenyl-3,8,13,17-tetramethyl-12-[(E)-2-nitroethenyl]porphyrin-2,18-diyl-kappa~4~N~21~,N~22~,N~23~,N~24~}dipro panoato(2-)]iron, ... (5 entities in total)
• Functional Keywords: nitrite, r-state human hemoglobin, nitriheme, oxygen transport
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 32409.53

Authors

Yi, J.,Thormas, L.M.,Richter-Addo, G.B. (deposition date: 2010-08-30, release date: 2011-09-07, Last modification date: 2023-09-06)

• Primary citation: Yi, J.,Thomas, L.M.,Musayev, F.N.,Safo, M.K.,Richter-Addo, G.B.; Crystallographic Trapping of Heme Loss Intermediates during the Nitrite-Induced Degradation of Human Hemoglobin.; Biochemistry, 50:8323-8332, 2011; PubMed: 21863786; DOI: 10.1021/bi2009322

Experimental method

X-RAY DIFFRACTION (2.1 Å)