3OGT

Design, Chemical synthesis, Functional characterization and Crystal structure of the sidechain analogue of 1,25-dihydroxyvitamin D3.

Summary for 3OGT

• Entry DOI: 10.2210/pdb3ogt/pdb
• Related: 1DB1
• Descriptor: Vitamin D3 receptor, (1S,3R,5Z,7E,14beta,17alpha,20S)-20-[5-(1-hydroxy-1-methylethyl)furan-2-yl]-9,10-secopregna-5,7,10-triene-1,3-diol, SULFATE ION, ... (4 entities in total)
• Functional Keywords: transcription factor, vitamin d, nucleus, transcription
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: P11473
• Total number of polymer chains: 1
• Total formula weight: 30024.61

Authors

Huet, T.,Fraga, R.,Mourino, A.,Moras, D.,Rochel, N. (deposition date: 2010-08-17, release date: 2011-08-17, Last modification date: 2024-02-21)

• Primary citation: Huet, T.,Fraga, R.,Mourino, A.,Moras, D.,Rochel, N.; Design, Chemical synthesis, Functional characterization and Crystal structure of the sidechain analogue of 1,25-dihydroxyvitamin D3.; To be Published,

Experimental method

X-RAY DIFFRACTION (1.75 Å)