3OG6

The crystal structure of human interferon lambda 1 complexed with its high affinity receptor in space group P212121

Summary for 3OG6

Entry DOI	10.2210/pdb3og6/pdb
Related	3G9V 3HHC 3OG4
Descriptor	Interleukin-29, Interleukin 28 receptor, alpha (Interferon, lambda receptor), beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	helical bundle, fibronectin type iii domain, beta-sandwich, cytokine signaling, membrane, cytokine-cytokine receptor complex, cytokine/cytokine receptor
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	48718.15
Authors	Miknis, Z.J.,Magracheva, E.,Lei, W.,Zdanov, A.,Kotenko, S.V.,Wlodawer, A. (deposition date: 2010-08-16, release date: 2010-10-20, Last modification date: 2023-09-06)
Primary citation	Miknis, Z.J.,Magracheva, E.,Li, W.,Zdanov, A.,Kotenko, S.V.,Wlodawer, A. Crystal structure of the complex of human interferon-lambda1 with its high affinity receptor interferon-lambdaR1. J.Mol.Biol., 404:650-664, 2010 Cited by PubMed: 20934432 DOI: 10.1016/j.jmb.2010.09.068 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.097 Å)

Structure validation