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3ODW

Crystal Structure of the Linker-DH/PH domains of p115-RhoGEF

Summary for 3ODW
Entry DOI10.2210/pdb3odw/pdb
Related1TXD 1X86 1XCG 3KZ1 3ODO 3ODX
DescriptorRho guanine nucleotide exchange factor 1 (1 entity in total)
Functional Keywordsregulation of rhoa gtpase, rhogef, dh, ph, rho, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: Q92888
Total number of polymer chains2
Total formula weight122158.70
Authors
Chen, Z.,Guo, L.,Sprang, S.R.,Sternweis, P.C. (deposition date: 2010-08-11, release date: 2011-01-05, Last modification date: 2023-09-06)
Primary citationChen, Z.,Guo, L.,Sprang, S.R.,Sternweis, P.C.
Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20:107-117, 2011
Experimental method
X-RAY DIFFRACTION (3.2 Å)
Structure validation

217705

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