3ODC

Human PARP-1 zinc finger 2 (Zn2) bound to DNA

Summary for 3ODC

• Entry DOI: 10.2210/pdb3odc/pdb
• Related: 3OD8 3ODA 3ODE
• Descriptor: Poly [ADP-ribose] polymerase 1, 5'-D(*CP*CP*CP*AP*GP*AP*CP*G)-3', 5'-D(*CP*GP*TP*CP*TP*GP*GP*G)-3', ... (5 entities in total)
• Functional Keywords: protein-dna complex, parp zinc finger, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus : P09874
• Total number of polymer chains: 6
• Total formula weight: 35284.52

Authors

Pascal, J.M.,Langelier, M.-F. (deposition date: 2010-08-11, release date: 2011-01-12, Last modification date: 2024-02-21)

• Primary citation: Langelier, M.F.,Planck, J.L.,Roy, S.,Pascal, J.M.; Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY.; J.Biol.Chem., 286:10690-10701, 2011; PubMed: 21233213; DOI: 10.1074/jbc.M110.202507

Experimental method

X-RAY DIFFRACTION (2.8 Å)