3OD4
Crystal Structure of Factor Inhibiting HIF-1 Alpha Complexed with Inhibitor
Summary for 3OD4
Entry DOI | 10.2210/pdb3od4/pdb |
Related | 1H2K 1H2L 1H2M 1H2N 1MZF 1YCI 2CGN 2CGO 2W0X 2WA3 2WA4 |
Descriptor | Hypoxia-inducible factor 1-alpha inhibitor, ZINC ION, 8-hydroxyquinoline-5-carboxylic acid, ... (6 entities in total) |
Functional Keywords | oxidoreductase, asparaginyl hydroxylase, dioxygenase, transcription, metal-binding, hif, iron, hydroxylation, oxygenase, nucleus, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus (Potential): Q9NWT6 |
Total number of polymer chains | 1 |
Total formula weight | 41239.42 |
Authors | King, O.N.F.,Bashford-Rogers, R.,Maloney, D.J.,Jadhav, A.,Heightman, T.D.,Simeonov, A.,Clifton, I.J.,McDonough, M.A.,Schofield, C.J. (deposition date: 2010-08-10, release date: 2011-07-06, Last modification date: 2024-03-20) |
Primary citation | King, O.N.F.,Bashford-Rogers, R.,Maloney, D.J.,Jadhav, A.,Heightman, T.D.,Simeonov, A.,Clifton, I.J.,McDonough, M.A.,Schofield, C.J. Crystal Structure of Factor Inhibiting HIF-1 Alpha Complexed with Inhibitor To be Published, |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
Download full validation report