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3O3A

Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-1

Summary for 3O3A
Entry DOI10.2210/pdb3o3a/pdb
Related2GT9 3O3B 3O3D 3O3E
DescriptorHLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Peptidomimetic ELA-1, ... (5 entities in total)
Functional Keywordsmart peptides, nonapeptide, mhc class i, hla-a2, peptidomimetics, cross-reactivity, immune system
Biological sourceHomo sapiens (human)
More
Cellular locationMembrane; Single-pass type I membrane protein: P01892
Secreted: P61769
Total number of polymer chains6
Total formula weight90250.28
Authors
Borbulevych, O.Y.,Baker, B.M. (deposition date: 2010-07-23, release date: 2010-12-08, Last modification date: 2023-11-15)
Primary citationDouat-Casassus, C.,Borbulevych, O.,Tarbe, M.,Gervois, N.,Jotereau, F.,Baker, B.M.,Quideau, S.
Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition.
J.Med.Chem., 53:7061-7066, 2010
Cited by
PubMed: 20806940
DOI: 10.1021/jm100683p
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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