3NYJ

Crystal Structure Analysis of APP E2 domain

Summary for 3NYJ

• Entry DOI: 10.2210/pdb3nyj/pdb
• Descriptor: Amyloid beta A4 protein, OSMIUM ION (3 entities in total)
• Functional Keywords: alzheimer's disease, helical hairpin, protein fibril
• Biological source: Homo sapiens (human)
• Cellular location: Membrane; Single-pass type I membrane protein: P05067
• Total number of polymer chains: 1
• Total formula weight: 24960.97

Authors

Ha, Y.,Hu, J.,Lee, S.,Liu, X. (deposition date: 2010-07-15, release date: 2011-06-01, Last modification date: 2017-11-08)

• Primary citation: Lee, S.,Xue, Y.,Hu, J.,Wang, Y.,Liu, X.,Demeler, B.,Ha, Y.; The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization.; Biochemistry, 50:5453-5464, 2011; PubMed: 21574595; DOI: 10.1021/bi101846x

Experimental method

X-RAY DIFFRACTION (3.2 Å)