3NXQ

Angiotensin Converting Enzyme N domain glycsoylation mutant (Ndom389) in complex with RXP407

Summary for 3NXQ

Entry DOI	10.2210/pdb3nxq/pdb
Related PRD ID	PRD_001050
Descriptor	Angiotensin-converting enzyme, TETRAETHYLENE GLYCOL, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
Functional Keywords	dicarboxy zinc metallopeptidase, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	150625.89
Authors	Anthony, C.S.,Corradi, H.R.,Schwager, S.L.U.,Redelinghuys, P.,Georgiadis, D.,Dive, V.,Acharya, K.R.,Sturrock, E.D. (deposition date: 2010-07-14, release date: 2010-09-08, Last modification date: 2020-07-29)
Primary citation	Anthony, C.S.,Corradi, H.R.,Schwager, S.L.,Redelinghuys, P.,Georgiadis, D.,Dive, V.,Acharya, K.R.,Sturrock, E.D. The N domain of human angiotensin-I-converting enzyme: the role of N-glycosylation and the crystal structure in complex with an N domain-specific phosphinic inhibitor, RXP407. J.Biol.Chem., 285:35685-35693, 2010 Cited by PubMed: 20826823 DOI: 10.1074/jbc.M110.167866 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.99 Å)

Structure validation