3NUN

phosphoinositide-dependent kinase-1 (PDK1) with lead compound

Summary for 3NUN

• Entry DOI: 10.2210/pdb3nun/pdb
• Related: 3NUS 3NUU 3NUY
• Descriptor: PkB-like, GLYCEROL, SULFATE ION, ... (5 entities in total)
• Functional Keywords: kinase domain, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 34956.83

Authors

Campobasso, N.,Ward, P. (deposition date: 2010-07-07, release date: 2011-06-22, Last modification date: 2011-07-13)

• Primary citation: Medina, J.R.,Blackledge, C.W.,Heerding, D.A.,Campobasso, N.,Ward, P.,Briand, J.,Wright, L.,Axten, J.M.; Aminoindazole PDK1 Inhibitors: A Case Study in Fragment-Based Drug Discovery; TO BE PUBLISHED,

Experimental method

X-RAY DIFFRACTION (2.2 Å)