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3NMS

Staphylococcal Complement Inhibitor (SCIN) in complex with Human Complement C3c

Summary for 3NMS
Entry DOI10.2210/pdb3nms/pdb
Related3L3O
DescriptorComplement C3, Staphylococcal complement inhibitor, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywordscomplement alternate pathway, complement pathway, convertase, immune response, inflammatory response, innate immunity, secreted, virulence, immune evasion, immune system
Biological sourceStaphylococcus aureus
More
Cellular locationSecreted: P01024 P01024 Q931M7 P01024
Total number of polymer chains4
Total formula weight144837.56
Authors
Geisbrecht, B.V.,Garcia, B.L. (deposition date: 2010-06-22, release date: 2010-08-04, Last modification date: 2023-12-27)
Primary citationGarcia, B.L.,Ramyar, K.X.,Tzekou, A.,Ricklin, D.,McWhorter, W.J.,Lambris, J.D.,Geisbrecht, B.V.
Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402:17-29, 2010
Cited by
PubMed: 20654625
DOI: 10.1016/j.jmb.2010.07.029
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (4.1 Å)
Structure validation

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