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3NJP

The Extracellular and Transmembrane Domain Interfaces in Epidermal Growth Factor Receptor Signaling

Summary for 3NJP
Entry DOI10.2210/pdb3njp/pdb
DescriptorEpidermal growth factor receptor, Epidermal growth factor, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywordsreceptor tyrosine kinase, transferase
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight151812.47
Authors
Lu, C.,Mi, L.-Z.,Grey, M.J.,Zhu, J.,Graef, E.,Yokoyama, S.,Springer, T.A. (deposition date: 2010-06-17, release date: 2010-10-13, Last modification date: 2023-09-06)
Primary citationLu, C.,Mi, L.Z.,Grey, M.J.,Zhu, J.,Graef, E.,Yokoyama, S.,Springer, T.A.
Structural evidence for loose linkage between ligand binding and kinase activation in the epidermal growth factor receptor.
Mol.Cell.Biol., 30:5432-5443, 2010
Cited by
PubMed: 20837704
DOI: 10.1128/MCB.00742-10
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.304 Å)
Structure validation

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