3NIG

The Closed Headpiece of Integrin IIb 3 and its Complex with an IIb 3 -Specific Antagonist That Does Not Induce Opening

Summary for 3NIG

• Entry DOI: 10.2210/pdb3nig/pdb
• Related: 2VDR 3NID 3NIF
• Descriptor: Integrin alpha-IIb, MAGNESIUM ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
• Functional Keywords: integrin, headpiece, alphaiib, beta3, cell adhesion-immune system complex, cell adhesion-blood clotting complex, cell adhesion/blood clotting
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 300994.33

Authors

Zhu, J.H.,Zhu, J.Q.,Springer, T.A. (deposition date: 2010-06-15, release date: 2010-12-22, Last modification date: 2023-09-06)

• Primary citation: Zhu, J.,Zhu, J.,Negri, A.,Provasi, D.,Filizola, M.,Coller, B.S.,Springer, T.A.; Closed headpiece of integrin {alpha}IIb{beta}3 and its complex with an {alpha}IIb{beta}3-specific antagonist that does not induce opening.; Blood, 116:5050-5059, 2010; PubMed: 20679525; DOI: 10.1182/blood-2010-04-281154

Experimental method

X-RAY DIFFRACTION (2.25 Å)