3NGA

Human CK2 catalytic domain in complex with CX-4945

Summary for 3NGA

Entry DOI	10.2210/pdb3nga/pdb
Descriptor	Casein kinase II subunit alpha, 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, SULFATE ION, ... (4 entities in total)
Functional Keywords	kinase, ck2, inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	81128.97
Authors	Ferguson, A.D. (deposition date: 2010-06-11, release date: 2010-12-15, Last modification date: 2024-02-21)
Primary citation	Ferguson, A.D.,Sheth, P.R.,Basso, A.D.,Paliwal, S.,Gray, K.,Fischmann, T.O.,Le, H.V. Structural basis of CX-4945 binding to human protein kinase CK2. Febs Lett., 585:104-110, 2011 Cited by PubMed: 21093442 DOI: 10.1016/j.febslet.2010.11.019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.71 Å)

Structure validation