3NDA

Crystal structure of serpin from tick Ixodes ricinus

Summary for 3NDA

Entry DOI	10.2210/pdb3nda/pdb
Descriptor	Serpin-2, PENTAETHYLENE GLYCOL (3 entities in total)
Functional Keywords	serpin, vaccination target, tick, hydrolase inhibitor
Biological source	Ixodes ricinus (Sheep tick)
Total number of polymer chains	2
Total formula weight	84533.72
Authors	Rezacova, P.,Kovarova, Z.,Chmelar, J.,Mares, M. (deposition date: 2010-06-07, release date: 2010-10-27, Last modification date: 2023-11-01)
Primary citation	Chmelar, J.,Oliveira, C.J.,Rezacova, P.,Francischetti, I.M.,Kovarova, Z.,Pejler, G.,Kopacek, P.,Ribeiro, J.M.,Mares, M.,Kopecky, J.,Kotsyfakis, M. A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation. Blood, 117:736-744, 2011 Cited by PubMed: 20940421 DOI: 10.1182/blood-2010-06-293241 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation