3N9R

Class II fructose-1,6-bisphosphate aldolase from helicobacter pylori in complex with N-(4-hydroxybutyl)-phosphoglycolohydroxamic acid, a competitive inhibitor

Summary for 3N9R

Entry DOI	10.2210/pdb3n9r/pdb
Related	3C4U 3C52 3C56 3N9S
Descriptor	Fructose-bisphosphate aldolase, ZINC ION, SODIUM ION, ... (6 entities in total)
Functional Keywords	fbp aldolase, class ii, inhibitor, lyase
Biological source	Helicobacter pylori
Total number of polymer chains	8
Total formula weight	273342.53
Authors	Coincon, M.,Sygusch, S. (deposition date: 2010-05-31, release date: 2010-11-17, Last modification date: 2023-09-06)
Primary citation	Daher, R.,Fonvielle, M.,Gest, P.M.,Guerin, M.E.,Jackson, M.,Sygusch, J.,Therisod, M. Rational Design, Synthesis, and Evaluation of New Selective Inhibitors of Microbial Class II (Zinc Dependent) Fructose Bis-phosphate Aldolases. J.Med.Chem., 53:7836-7842, 2010 Cited by PubMed: 20929256 DOI: 10.1021/jm1009814 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation