3N0I

Crystal Structure of Ad37 fiber knob in complex with GD1a oligosaccharide

Summary for 3N0I

Entry DOI	10.2210/pdb3n0i/pdb
Descriptor	Fiber, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ZINC ION, ... (4 entities in total)
Functional Keywords	adenovirus, fiber knob, ganglioside, gd1a, virus-receptor complex, oligosaccharide structure, protein carbohydrate interaction, cell adhesion
Biological source	Human adenovirus 37
Total number of polymer chains	3
Total formula weight	66635.97
Authors	Nilsson, E.C.,Storm, R.J.,Bauer, J.,Johansson, S.M.C.,Lookene, A.,Angstroem, J.,Hedenstroem, M.,Fraengsmyr, L.,Rinaldi, S.,Willison, H.,Domelloef, F.P.,Stehle, T.,Arnberg, N. (deposition date: 2010-05-14, release date: 2010-12-29, Last modification date: 2023-09-06)
Primary citation	Nilsson, E.C.,Storm, R.J.,Bauer, J.,Johansson, S.M.,Lookene, A.,Angstrom, J.,Hedenstrom, M.,Eriksson, T.L.,Frangsmyr, L.,Rinaldi, S.,Willison, H.J.,Domellof, F.P.,Stehle, T.,Arnberg, N. The GD1a glycan is a cellular receptor for adenoviruses causing epidemic keratoconjunctivitis. NAT.MED. (N.Y.), 17:105-109, 2011 Cited by PubMed: 21151139 DOI: 10.1038/nm.2267 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation