3MZW

HER2 extracelluar region with affinity matured 3-helix affibody ZHER2:342

Summary for 3MZW

Entry DOI	10.2210/pdb3mzw/pdb
Descriptor	Tyrosine kinase-type cell surface receptor HER2, Immunoglobulin G-binding protein A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	protein-protein complex, transferase
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	76375.46
Authors	Eigenbrot, C.,Ultsch, M.H. (deposition date: 2010-05-13, release date: 2010-07-28, Last modification date: 2023-09-06)
Primary citation	Eigenbrot, C.,Ultsch, M.,Dubnovitsky, A.,Abrahmsen, L.,Hard, T. Structural basis for high-affinity HER2 receptor binding by an engineered protein. Proc.Natl.Acad.Sci.USA, 107:15039-15044, 2010 Cited by PubMed: 20696930 DOI: 10.1073/pnas.1005025107 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation