3MZ3
Crystal structure of Co2+ HDAC8 complexed with M344
Summary for 3MZ3
Entry DOI | 10.2210/pdb3mz3/pdb |
Related | 1T67 3EW8 3MZ4 3MZ6 3MZ7 |
Descriptor | Histone deacetylase 8, COBALT (II) ION, POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | hydrolase, metalloenzyme, arginase-fold |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q9BY41 |
Total number of polymer chains | 2 |
Total formula weight | 87353.02 |
Authors | Dowling, D.P.,Gattis, S.G.,Fierke, C.A.,Christianson, D.W. (deposition date: 2010-05-11, release date: 2010-06-23, Last modification date: 2023-09-06) |
Primary citation | Dowling, D.P.,Gattis, S.G.,Fierke, C.A.,Christianson, D.W. Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function. Biochemistry, 49:5048-5056, 2010 Cited by PubMed: 20545365DOI: 10.1021/bi1005046 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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