3MUV

Crystal Structure of the G20A/C92U mutant c-di-GMP riboswith bound to c-di-AMP

Summary for 3MUV

Entry DOI	10.2210/pdb3muv/pdb
Related	3IRW 3MUM 3MUR 3MUT 3MXH
Descriptor	U1 small nuclear ribonucleoprotein A, G20A/C92U mutant c-di-GMP riboswitch, (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ... (5 entities in total)
Functional Keywords	rna, riboswitch, c-di-amp, c-di-gmp, rna binding protein-rna complex, rna binding protein/rna
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: P09012
Total number of polymer chains	2
Total formula weight	41950.79
Authors	Strobel, S.A.,Smith, K.D. (deposition date: 2010-05-03, release date: 2010-08-25, Last modification date: 2023-09-06)
Primary citation	Smith, K.D.,Lipchock, S.V.,Livingston, A.L.,Shanahan, C.A.,Strobel, S.A. Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch . Biochemistry, 49:7351-7359, 2010 Cited by PubMed: 20690679 DOI: 10.1021/bi100671e PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation