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3MR5

Human DNA polymerase eta - DNA ternary complex with a CPD 1bp upstream of the active site (TT3)

Summary for 3MR5
Entry DOI10.2210/pdb3mr5/pdb
Related3MR2 3MR3 3MR4 3MR6
DescriptorDNA polymerase eta, DNA (5'-D(*TP*AP*AP*CP*(TTD)P*AP*TP*GP*AP*CP*GP*A)-3'), DNA (5'-D(*AP*CP*GP*TP*CP*AP*TP*AP*A)-3'), ... (7 entities in total)
Functional Keywordspol eta, polymerase, thymine dimer, cpd, xpv, xeroderma pigmentosum variant, dna damage, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus: Q9Y253
Total number of polymer chains3
Total formula weight57390.19
Authors
Biertumpfel, C.,Zhao, Y.,Ramon-Maiques, S.,Gregory, M.T.,Lee, J.Y.,Yang, W. (deposition date: 2010-04-28, release date: 2010-06-30, Last modification date: 2024-02-21)
Primary citationBiertumpfel, C.,Zhao, Y.,Kondo, Y.,Ramon-Maiques, S.,Gregory, M.,Lee, J.Y.,Masutani, C.,Lehmann, A.R.,Hanaoka, F.,Yang, W.
Structure and mechanism of human DNA polymerase eta.
Nature, 465:1044-1048, 2010
Cited by
PubMed: 20577208
DOI: 10.1038/nature09196
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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