3MN5

Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation

Summary for 3MN5

Entry DOI	10.2210/pdb3mn5/pdb
Related	1IJJ 3MMV 3MN6 3MN7 3MN9
Descriptor	Actin, alpha skeletal muscle, Protein spire, CALCIUM ION, ... (6 entities in total)
Functional Keywords	wh2 domain, spire, actin complex, contractile protein-protein binding complex, contractile protein/protein binding
Biological source	Drosophila melanogaster (Fruit fly) More
Cellular location	Cytoplasm, cytoskeleton: P68135 Q9U1K1
Total number of polymer chains	2
Total formula weight	45342.33
Authors	Ducka, A.M.,Sitar, T.,Popowicz, G.M.,Huber, R.,Holak, T.A. (deposition date: 2010-04-21, release date: 2010-06-02, Last modification date: 2023-09-06)
Primary citation	Ducka, A.M.,Joel, P.,Popowicz, G.M.,Trybus, K.M.,Schleicher, M.,Noegel, A.A.,Huber, R.,Holak, T.A.,Sitar, T. Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation. Proc.Natl.Acad.Sci.USA, 107:11757-11762, 2010 Cited by PubMed: 20538977 DOI: 10.1073/pnas.1005347107 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation