3MIA

Crystal structure of HIV-1 Tat complexed with ATP-bound human P-TEFb

Summary for 3MIA

• Entry DOI: 10.2210/pdb3mia/pdb
• Related: 3MI9
• Descriptor: Cell division protein kinase 9, Cyclin-T1, Protein Tat, ... (7 entities in total)
• Functional Keywords: p-tefb, cdk9, cyclin t1, hiv-1, tat, protein binding
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P50750 O60563; Host nucleus, host nucleolus: P04608
• Total number of polymer chains: 3
• Total formula weight: 82079.12

Authors

Tahirov, T.H.,Babayeva, N.D.,Varzavand, K.,Cooper, J.J.,Sedore, S.C.,Price, D.H. (deposition date: 2010-04-09, release date: 2010-06-09, Last modification date: 2023-09-06)

• Primary citation: Tahirov, T.H.,Babayeva, N.D.,Varzavand, K.,Cooper, J.J.,Sedore, S.C.,Price, D.H.; Crystal structure of HIV-1 Tat complexed with human P-TEFb.; Nature, 465:747-751, 2010; PubMed: 20535204; DOI: 10.1038/nature09131

Experimental method

X-RAY DIFFRACTION (3 Å)