3MDC

DNA polymerase lambda in complex with dFdCTP

Summary for 3MDC

• Entry DOI: 10.2210/pdb3mdc/pdb
• Related: 3MDA
• Descriptor: DNA polymerase lambda, DNA (5'-D(*CP*GP*GP*CP*GP*GP*TP*AP*CP*TP*G)-3'), DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), ... (8 entities in total)
• Functional Keywords: protein-dna complex, lyase, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : Q9UGP5
• Total number of polymer chains: 4
• Total formula weight: 43424.52

Authors

Garcia-Diaz, M.,Murray, M.,Kunkel, T.,Chou, K.M. (deposition date: 2010-03-30, release date: 2010-04-28, Last modification date: 2024-02-21)

• Primary citation: Garcia-Diaz, M.,Murray, M.S.,Kunkel, T.A.,Chou, K.M.; Interaction between DNA Polymerase lambda and anticancer nucleoside analogs.; J.Biol.Chem., 285:16874-16879, 2010; PubMed: 20348107; DOI: 10.1074/jbc.M109.094391

Experimental method

X-RAY DIFFRACTION (1.999 Å)