5WCM

Crystal structure of the complex between class B3 beta-lactamase BJP-1 and 4-nitrobenzene-sulfonamide - new refinement

Replaces:  3M8T

Summary for 5WCM

• Entry DOI: 10.2210/pdb5wcm/pdb
• Descriptor: Blr6230 protein, ZINC ION, 4-nitrobenzenesulfonamide, ... (4 entities in total)
• Functional Keywords: hydrolase, zinc enzyme, sulfonamide complex, hydrolase-inhibitor complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
• Total number of polymer chains: 2
• Total formula weight: 58559.50

Authors

Docquier, J.D.,Benvenuti, M.,Calderone, V.,Menciassi, N.,Shabalin, I.G.,Raczynska, J.E.,Wlodawer, A.,Jaskolski, M.,Minor, W.,Mangani, S. (deposition date: 2017-06-30, release date: 2017-07-19, Last modification date: 2023-10-04)

• Primary citation: Docquier, J.D.,Benvenuti, M.,Calderone, V.,Stoczko, M.,Menciassi, N.,Rossolini, G.M.,Mangani, S.; High-resolution crystal structure of the subclass B3 metallo-beta-lactamase BJP-1: rational basis for substrate specificity and interaction with sulfonamides.; Antimicrob. Agents Chemother., 54:4343-4351, 2010; PubMed: 20696874; DOI: 10.1128/AAC.00409-10

Experimental method

X-RAY DIFFRACTION (1.2 Å)