3M6G

Crystal structure of actin in complex with lobophorolide

Summary for 3M6G

Entry DOI	10.2210/pdb3m6g/pdb
Related	1QZ5 1YXQ 2ASM 2ASO 2ASP 2VYP
Descriptor	Actin, alpha skeletal muscle, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
Functional Keywords	actin, macrolide, lobophorolide, actin dimer, marine toxin, atp-binding, cytoskeleton, muscle protein, nucleotide-binding, structural protein
Biological source	Oryctolagus cuniculus (rabbit)
Cellular location	Cytoplasm, cytoskeleton: P68135
Total number of polymer chains	2
Total formula weight	85409.12
Authors	Allingham, J.S. (deposition date: 2010-03-15, release date: 2010-09-08, Last modification date: 2024-03-13)
Primary citation	Blain, J.C.,Mok, Y.F.,Kubanek, J.,Allingham, J.S. Two molecules of lobophorolide cooperate to stabilize an actin dimer using both their "ring" and "tail" region. Chem.Biol., 17:802-807, 2010 Cited by PubMed: 20797609 DOI: 10.1016/j.chembiol.2010.06.010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation