3LWB

Crystal Structure of apo D-alanine:D-alanine Ligase (Ddl) from Mycobacterium tuberculosis

Summary for 3LWB

• Entry DOI: 10.2210/pdb3lwb/pdb
• Descriptor: D-alanine--D-alanine ligase, NITRATE ION (3 entities in total)
• Functional Keywords: d-alanine--d-alanine ligase, ddl, d-alanyl--d-alanine ligase, rv2981c, d-alanine, structural genomics, tb structural genomics consortium, tbsgc, atp-binding, cell shape, cell wall biogenesis, degradation, ligase, magnesium, manganese, metal-binding, nucleotide-binding, peptidoglycan synthesis
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 2
• Total formula weight: 79632.35

Authors

Bruning, J.B.,Murillo, A.C.,Chacon, O.,Barletta, R.G.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2010-02-23, release date: 2010-03-09, Last modification date: 2023-09-06)

• Primary citation: Bruning, J.B.,Murillo, A.C.,Chacon, O.,Barletta, R.G.,Sacchettini, J.C.; Structure of the Mycobacterium tuberculosis D-Alanine:D-Alanine Ligase, a Target of the Antituberculosis Drug D-Cycloserine.; Antimicrob.Agents Chemother., 55:291-301, 2011; PubMed: 20956591; DOI: 10.1128/AAC.00558-10

Experimental method

X-RAY DIFFRACTION (2.1 Å)