3LUH

Crystal structure of MID domain from hAGO2 in complex with GMP

Summary for 3LUH

Entry DOI	10.2210/pdb3luh/pdb
Related	3luc 3lud 3lug 3luj 3luk
Descriptor	Protein argonaute-2, GUANOSINE-5'-MONOPHOSPHATE, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	mid domain, ribonucleoprotein, rna-binding, rna-mediated gene silencing, translation regulation, rna binding protein
Biological source	Homo sapiens (human)
Total number of polymer chains	3
Total formula weight	47162.50
Authors	Frank, F.,Sonenberg, N.,Nagar, B. (deposition date: 2010-02-17, release date: 2010-05-26, Last modification date: 2024-02-21)
Primary citation	Frank, F.,Sonenberg, N.,Nagar, B. Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2. Nature, 465:818-822, 2010 Cited by PubMed: 20505670 DOI: 10.1038/nature09039 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.999 Å)

Structure validation