3LUE

Model of alpha-actinin CH1 bound to F-actin

Summary for 3LUE

• Entry DOI: 10.2210/pdb3lue/pdb
• EMDB information: 5170
• Descriptor: Actin, cytoplasmic 1, Alpha-actinin-3 (2 entities in total)
• Functional Keywords: calponin homology domains, acetylation, atp-binding, cytoplasm, cytoskeleton, methylation, nucleotide-binding, phosphoprotein, actin-binding, calcium, polymorphism, structural protein, deafness, disease mutation, dystonia
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 20
• Total formula weight: 541231.77

Authors

Galkin, V.E.,Orlova, A.,Salmazo, A.,Djinovic-Carugo, K.,Egelman, E.H. (deposition date: 2010-02-17, release date: 2010-04-28, Last modification date: 2024-02-21)

• Primary citation: Galkin, V.E.,Orlova, A.,Salmazo, A.,Djinovic-Carugo, K.,Egelman, E.H.; Opening of tandem calponin homology domains regulates their affinity for F-actin.; Nat.Struct.Mol.Biol., 17:614-616, 2010; PubMed: 20383143; DOI: 10.1038/nsmb.1789

Experimental method

ELECTRON MICROSCOPY (15 Å)