3LRU

hPRP8 Non-Native Subdomain

Summary for 3LRU

Entry DOI	10.2210/pdb3lru/pdb
Descriptor	Pre-mRNA-processing-splicing factor 8 (2 entities in total)
Functional Keywords	alternate folding of protein, disease mutation, mrna processing, mrna splicing, nucleus, phosphoprotein, retinitis pigmentosa, ribonucleoprotein, rna-binding, sensory transduction, spliceosome, vision, rna binding protein
Biological source	Homo sapiens (human)
Cellular location	Nucleus speckle : Q6P2Q9
Total number of polymer chains	2
Total formula weight	36881.32
Authors	Schellenberg, M.J.,Ritchie, D.B.,MacMillan, A.M. (deposition date: 2010-02-11, release date: 2010-08-25, Last modification date: 2024-02-21)
Primary citation	Schellenberg, M.J.,Ritchie, D.B.,Wu, T.,Markin, C.J.,Spyracopoulos, L.,MacMillan, A.M. Context-dependent remodeling of structure in two large protein fragments. J.Mol.Biol., 402:720-730, 2010 Cited by PubMed: 20713060 DOI: 10.1016/j.jmb.2010.08.020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation