3LMY

The Crystal Structure of beta-hexosaminidase B in complex with Pyrimethamine

Summary for 3LMY

• Entry DOI: 10.2210/pdb3lmy/pdb
• Related: 1NOU 1NOW 1NP0 2GJX 2GK1
• Descriptor: Beta-hexosaminidase subunit beta, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: 6-stranded anti-parallel beta-sheet, tim barrel, disease mutation, disulfide bond, gangliosidosis, glycoprotein, glycosidase, hydrolase, lysosome
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 129070.59

Authors

Bateman, K.S.,Cherney, M.M.,Withers, S.G.,Mahuran, D.J.,Tropak, M.,James, M.N.G. (deposition date: 2010-02-01, release date: 2011-02-16, Last modification date: 2023-09-06)

• Primary citation: Bateman, K.S.,Cherney, M.M.,Withers, S.G.,Mahuran, D.J.,Tropak, M.,James, M.N.G.; The Crystal Structure of beta-hexosaminidase B in complex with Pyrimethamine; To be Published,

Experimental method

X-RAY DIFFRACTION (2.8 Å)