3LLR

Crystal structure of the PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 alpha

Summary for 3LLR

Entry DOI	10.2210/pdb3llr/pdb
Descriptor	DNA (cytosine-5)-methyltransferase 3A, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, ... (4 entities in total)
Functional Keywords	transferase, dna methyltransferase, methylysine binding, structural genomics consortium, sgc, alternative promoter usage, chromatin regulator, dna-binding, metal-binding, methyltransferase, nucleus, phosphoprotein, repressor, s-adenosyl-l-methionine, zinc-finger
Biological source	Homo sapiens (human)
Cellular location	Nucleus : Q9Y6K1
Total number of polymer chains	5
Total formula weight	87444.76
Authors	Qiu, W.,Dombrovski, L.,Ni, S.,Weigelt, J.,Boutra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Wu, H.,Structural Genomics Consortium (SGC) (deposition date: 2010-01-29, release date: 2010-03-23, Last modification date: 2023-09-06)
Primary citation	Wu, H.,Zeng, H.,Lam, R.,Tempel, W.,Amaya, M.F.,Xu, C.,Dombrovski, L.,Qiu, W.,Wang, Y.,Min, J. Structural and histone binding ability characterizations of human PWWP domains. Plos One, 6:e18919-e18919, 2011 Cited by PubMed: 21720545 DOI: 10.1371/journal.pone.0018919 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation