3LLM

Crystal Structure Analysis of a RNA Helicase

Summary for 3LLM

• Entry DOI: 10.2210/pdb3llm/pdb
• Descriptor: ATP-dependent RNA helicase A, MANGANESE (II) ION, CACODYLATE ION, ... (6 entities in total)
• Functional Keywords: alpha-beta-alpha, structural genomics, structural genomics consortium, sgc, activator, atp-binding, dna-binding, helicase, hydrolase, methylation, nucleotide-binding, nucleus, phosphoprotein, rna-binding
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus, nucleolus: Q08211
• Total number of polymer chains: 2
• Total formula weight: 54724.93

Authors

Schutz, P.,Karlberg, T.,Collins, R.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, A.,Johansson, I.,Kallas, A.,Kraulis, P.,Kotenyova, T.,Kotzsch, A.,Markova, N.,Moche, M.,Nielsen, T.K.,Nordlund, P.,Nyman, T.,Persson, C.,Roos, A.K.,Siponen, M.I.,Svensson, L.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Wahlberg, E.,Weigelt, J.,Welin, M.,Wisniewska, M.,Schuler, H.M.,Structural Genomics Consortium (SGC) (deposition date: 2010-01-29, release date: 2010-05-12, Last modification date: 2011-07-13)

• Primary citation: Schutz, P.,Wahlberg, E.,Karlberg, T.,Hammarstrom, M.,Collins, R.,Flores, A.,Schuler, H.; Crystal structure of human RNA helicase A (DHX9): structural basis for unselective nucleotide base binding in a DEAD-box variant protein.; J.Mol.Biol., 400:768-782, 2010; PubMed: 20510246; DOI: 10.1016/j.jmb.2010.05.046

Experimental method

X-RAY DIFFRACTION (2.8 Å)